Article Contents ::
Details About Generic Salt :: Zanamivir
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 13N. ANTI-RETROVIRALS (DRUGS FOR HIV) in 13. ANTI-INFECTIVES |
| ZANAMIVIR |
| NEURAMINIDASE INHIBITOR | ANTI-VIRAL |
| PK: A: Poor M: None E: Urine & feces |
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Indications & Dose: INFLUENZA A & B Inh Adult 10mg BID 5 days starts within 48h after onset of symptoms Child 10mg BID 5 days starts within 36-48h after onset of symptoms | Prophylactic therapy Inh Adult Post-exposure prophylaxis: 10mg OD 10days starts within 36h of exposure, seasonal prophylaxis: 10mg OD 28 days & treatment starts within 5days of outbreak Child >5 yr: Post-exposure prophylaxis: Same as adult dose |
| Contra: Hypersensitivity, asthma/COPD
Precautions: chronic respiratory diseases ADR: Serious: hypersensitivity, oropharyngeal edema, severe skin rashes, delirium, acute bronchospasm/decline respiratory function, arrhythmia, SJS, TEN, syncope, Others: headache, GI symptoms, cough, bronchitis, fever/chills, malaise, dizziness, anorexia, myalgia DDI: Serious Influenza vaccines efficacy is reduced Monitor: Abnormal behaviour |