The Brand Name AZTATIN Has Generic Salt :: Lovastatin
AZTATIN Is From Company Sun Priced :: Rs. 31.00/55.50
AZTATIN have Lovastatin is comes under Sub class Anti Hyperlipidemics of Main Class Cardiovascular System
Main Medicine Class:: Cardiovascular System Sub Medicine Class :: Anti Hyperlipidemics
| Salt Name : OR Generic Name | Form | Price : MRP /Probable | Packing | ||
| Lovastatin | TAB | Rs. 31.00/55.50 | 10-Oct |
| Brand Name | Company / Manufacturers | Strength | Unit | Price / 10-Oct |
| AZTATIN | Sun | 10/20;MG | 10-Oct | Rs. 31.00/55.50 |
| Company Brand Name | Salt Combination | Main Medical Class | Sub Medical Class |
| From Sun :: AZTATIN | Lovastatin | Cardiovascular System | Anti Hyperlipidemics |
Indications for Drugs ::
Coronary Artery Disease, Hyperlipidaemias
Drug Dose ::
Adult: PO Hyperlipidaemias; Primary prevention of coronary artery disease Initial: 10-20 mg/day at bedtime, may increase 4-wkly if needed. Max: 80 mg/day (immediate-release); 60 mg/day (extended-release).
Contraindication ::
Active liver disease; unexplained persistently elevated serum transaminases. Pregnancy and lactation.
Drug Precautions ::
Renal impairment; inadequately controlled hypothyroidism; history of liver disease; alcoholism; patients at risk of rhabdomyolysis. Elderly. Monitor LFTs.
Drug Side Effects ::
Increased creatine phosphokinase; flatulence, nausea, dyspepsia, constipation or diarrhoea, abdominal pain; muscle cramps, myalgia, weakness; blurred vision; headache, dizziness; rash. Potentially Fatal: Rhabdomyolysis and acute renal failure.
Pregnancy category ::
5
Drug Mode of Action ::
Lovastatin reduces cholesterol by competitively inhibiting HMG-CoA reductase, the rate-limiting step cholesterol biosynthesis.
Drug Interactions ::
Increased risk of myopathy/rhabdomyolysis w/ amiodarone, colchicine, ranolazine, danazol, diltiazem and verapamil. May increase anticoagulant effect of warfarin. Potentially Fatal: Increased risk of myopathy and rhabdomyolysis w/ concomitant CYP3A4 inhibitors (e.g. nefazodone, erythromycin, boceprevir, clarithromycin, telithromycin, HIV protease inhibitors, itraconazole, ketoconazole, posaconazole, telaprevir), gemfibrozil, ciclosporin.