Aceclofenac

Details About Generic Salt ::  Aceclofenac 

Main Medicine Class:: Musculoskeletal Disorders , Pain   Sub Medicine Class ::  Analgesics , Anti inflammatory Drugs

12E. ANALGESICS & ANTI-INFLAMMATORY DRUGS in 12. MUSCULOSKELETAL DISORDERS & PAIN
ACECLOFENAC
PHENYLACETIC ACID DERIVATIVE, NSAID | ANALGESIC & ANTI-INFLAMMATORY
PK: A: Rapid & complete D: 25L M: Liver E: Urine

Indications & Dose: ANKYLOSING SPONDYLITIS PO Adult 100mg bid | OSTEOARTHRITIS PO Adult 100mg bid | RHEUMATOID ARTHRITIS PO Adult 100mg bid

Contra: severe HF, active/suspected peptic ulcer/GI bleeding, children, moderate/severe renal impairment, sensitivity to aceclofenac/other nsaids, previous aspirin/nsaid-related allergic/anaphylactic reactions, liver impairment

Precautions: coagulation defects, HTN, asthma/allergic disorders, elderly

ADR: Serious: PUD, severe gi bleeding, hypersensitivity reactions, aseptic meningitis, hepatotoxicity, visual disturbances, nephrotoxicity, blood disorders, alveolitis, photosensitivity, pulmonary eosinophilia, pancreatitis, SJS, TEN, Colitis, fluid retention, Others: GI disturbances, headache, vertigo, dizziness, nervousness, tinnitus, drowsiness, insomnia

DDI: Serious Quinolones causes convulsions, Other NSAIDs increases frequency of adverse effects, Coumarins increases risk of bleeding, Diuretics/Ciclosporin increases risk of nephrotoxicity, Methotrexate/Digoxin levels are increased, Lithium toxicity raises

Diet: After food

Monitor: Renal & hepatic function, CBC

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