The Brand Name ANTI-THYROX Has Generic Salt :: Carbimazole
ANTI-THYROX Is From Company Macleods Priced :: Rs. 83.44
ANTI-THYROX have Carbimazole is comes under Sub class Thyroid , Anti Thyroid Drugs of Main Class Endocrine,Steroid Hormones , Metabolic System
Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System Sub Medicine Class :: Thyroid , Anti Thyroid Drugs
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Indications for Drugs ::
Grave’s disease, Hyperthyroidism, Diabetic nephropathy, Preparation for thyroidectomy
Drug Dose ::
Oral Hyperthyroidism, Adjunct to radio-iodine therapy, Grave’s disease, Preparation for thyroidectomy Adult: Initially, 20-60 mg daily as a single or divided dose, reduced gradually once euthyroidism is achieved. Maintenance: 5-15 mg daily for at least 1 yr or 18 mth. Child: 4-12 yr: Initially, 15 mg daily.
Hyperthyroidism due to nodular goitre.
Drug Precautions ::
Liver diseases, pregnancy, lactation.
Drug Side Effects ::
Mild leucopaenia, sore throat, mouth ulcers, fever, bruising, malaise; rarely cholestatic jaundice; nephrotic syndrome. Nausea, loss of taste, headache, arthralgia, alopoecia. Potentially Fatal: Agranulocytosis, aplastic anaemia, hypoprothrombinaemia, neutropaenia; hypothyroidism and goitre.
Pregnancy category ::
Drug Mode of Action ::
Carbimazole is metabolised to methimazole which is responsible for its antithyroid action. It blocks the production of thyroid hormones by inhibiting thyroid peroxidase.
Drug Interactions ::
Potentially Fatal: Increased sensitivity to warfarin in hyperthyroidism and careful control required as patient is rendered euthyroid.