Astemizole

Details About Generic Salt ::  Astemizole 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Anti Histamines and Nasal Decongestants

6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM
ASTEMIZOLE
H1-BLOCKER (SECOND GENERATION) | ANTI-ALLERGIC
PK: A: Rapid M: Hepatic E: Urine, feces

Indications & Dose: ALLERGIC RHINITIS PO Child 6-12yr: 5mg OD

Contra: cardiac/significant hepatic disease, drugs, hypokalaemia/electrolyte imbalances

Precautions: polypharmacy

ADR: Serious: ventricular arrhythmias, Others: increased appetite & weight gain

DDI: Serious HIV protease inhibitors leads to arrhythmias, Azoles leads to Torsade de pointes, Macrolides leads to Torsade de pointes arrhythmias, Nefazodone prolongs QT interval