Bacitracin

Details About Generic Salt ::  Bacitracin 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

13R. MISCELLANEOUS in 13. ANTI-INFECTIVES
BACITRACIN
BACTERICIDAL | ANTI-INFECTIVE (TOPICAL)
also comes under 3C. Anti-Infectives in 3. Ocular
PK: A: Rapid (IM) E: Urine

Indications & Dose: ANTIBIOTIC-ASSOCIATED COLITIS PO Adult 25, 000U QID 7-10 days | EMPYEMA IM Child Infants: <2.5 kg: 900U/kg/day in 2-3 divided doses, >2.5 kg: 1000U/kg/day in 2-3 divided doses | STAPHYLOCOCCAL PNEUMONIA IM Child Infants: <2.5 kg: 900U/kg/day in 2-3 divided doses, >2.5 kg: 1000U/kg/day in 2-3 divided doses | SUSCEPTIBLE BACTERIAL INFECT Acute TP Adult Ophthalmic (500U/g): Instill 1/4” to 1/2” ribbon q3-4h into conjunctival sac Child Same as adult dose | Mild-to-moderate TP Adult Ophthalmic (500U/g): Instill 1/4” to 1/2” ribbon 2-3 times/day into conjunctival sac 7-10 days Child Same as adult dose

Precautions: withdraw bacitracin if renal toxicity occurs, avoid concomitant therapy with nephrotoxic drugs

ADR: Serious: tubular & glomerular necrosis, anaphylaxis, Others: nausea, vomiting, pain at Inj site, rashes

DDI: Serious Vancomycin increases risk of nephrotoxicity

Monitor: Fluid intake & urinary output

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