The Brand Name BUPIVAN Has Generic Salt :: Bupivacaine 

BUPIVAN  Is From Company Globus Priced :: Rs. 21.5

BUPIVAN have Bupivacaine is comes under Sub class Local Anesthetics of  Main Class Anesthetics

Main Medicine Class:: Anesthetics  Sub Medicine Class :: Local Anesthetics 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Bupivacaine  INJ  Rs. 21.5  20ML V.
Brand Name Company / Manufacturers Strength Unit Price / 20ML V.
 BUPIVAN  Globus  0.25%  20ML V. Rs. 21.5

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Globus :: BUPIVAN  Bupivacaine  Anesthetics Local Anesthetics

Indications for Drugs ::

Local anesthesia, Epidural, Intrathecal anesthesia, Epidural analgesia

Drug Dose ::

Adult: Inj Percutaneous infiltration anesth For prolonged action: 9 mg w/ adrenaline (1 in 200,000), may repeat 2-10 mins later if needed. Max: 90 mg per dental sitting. Peripheral nerve block 12.5 mg (as 0.25% soln) or 25 mg (as 0.5% soln) . Max: 150 mg/dose. Sympathetic nerve block As 0.25% soln: 50-125 mg. Retrobulbar block As 0.75% soln: 15-30 mg. Caudal block In surgery: 37.5-75 mg (as 0.25% soln) or 75-150 mg (as 0.5% soln). Lumbar epidural block In surgery: 25-50 mg (as 0.25% soln) and 50-100 mg (as 0.5% soln).

Contraindication ::

Hypersensitivity to local anaesthetics of amide type. IV regional anaesthesia; paracervical block in obstetrics; spinal anaesthesia <18 yr. Lactation. Solutions containing preservatives for caudal or epidural block. Drug Precautions ::

Hepatic disease; CV disease; children <12 yr; pregnancy. Elderly and debilitated patients. Drug Side Effects ::

CNS excitation may be followed by depression. Hypotension, bradycardia, arrhythmias and cardiac arrest; methaemoglobinaemia; seizures, restlessness, dizziness. Hypersensitivity. Prolonged block. Potentially Fatal: Cardiac and sudden respiratory arrest.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Bupivacaine blocks both the initiation and conduction of nerve impulses reducing the permeability of neuronal membranes to Na ions resulting in inhibition of depolarization w/ resultant blockade of conduction.

Drug Interactions ::

Additive systemic toxic effect w/ other local anaesth or agents structurally related to amide-type local anaesth (e.g. lidocaine and mexiletine). Increased risk of myocardial depression w/ antiarrhythmics. Enhanced adverse effects w/ hyaluronidase. Decreased clearance resulting to increased plasma concentrations w/ cimetidine and ranitidine. Increased risk of adverse effects w/ ?-blockers and Ca channel blockers.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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