Ceftriaxone , Tazobactam

Details About Generic Salt ::  Ceftriaxone , Tazobactam 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Cephalosporins

13B. CEPHALOSPORINS in 13. ANTI-INFECTIVES
CEFTRIAXONE + TAZOBACTAM
CEPHALOSPORIN, ß-LACTAMASE INHIBITOR | ANTI-INFECTIVE

Indications & Dose: BACTERIAL OTITIS MEDIA Acute IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child IM: 56.25mg/kg OD max 1.125g | BACTERIAL SEPTICEMIA IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg/day in divided doses q12h max 2.250g | BONE & JOINT INFECT IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg/day in divided doses q12h max 2.250g | GONORRHEA Uncomplicated IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg/day in divided doses q12h max 2.250g | INTRA-ABDOMINAL INFECT IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg/day in divided doses q12h max 2.250g | LOWER RESPIRATORY TRACT INFECT IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg/day in divided doses q12h max 2.250g | MENINGITIS IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 112.5mg/kg 7-14d OD or divided doses q12h max 4.5g | PELVIC INFLAMMATORY DISEASE IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg/day in divided doses q12h max 2.250g | SKIN/SKIN STRUCTURE INFECT IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg OD or in equally divided doses max 2.250g/day | SURGICAL PROPHYLAXIS Post-operative prophylaxis IV General 1.125g single dose before 30-120min prior to surgery | URINARY TRACT INFECT IV/IM Adult 1.125-2.250g OD/BID (based on severity of infect) max 4.5g/day Child 56.25-84.375mg/kg/day in divided doses q12h max 2.250g

Contra: Hypersensitivity, hyperbilirubinemic neonates

Precautions: Penicillin-sensitive patients, history of allergy, renal/hepatic impairment, history of GI disease, discontinue drug if signs & symptoms suggestive of gallbladder disease seen

ADR: Serious: Blood disorders, elevations of SGOT/AST/SGPT/ALT, elevations of BUN, allergic pneumonitis, anaphylaxis, bronchospasm, hematuria, jaundice, nephrolithiasis, seizures, decrease in the prothrombin time, palpitations, moniliasis/vaginitis, Others: diaphoresis, abdominal pain, Phlebitis, local reactions, rash, headache, dizziness, diarrhea, nausea, vomiting

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