Cetirizine

Details About Generic Salt ::  Cetirizine 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Anti Histamines and Nasal Decongestants

6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM
CETIRIZINE
H1-BLOCKER (SECOND GENERATION) | ANTI-ALLERGIC
also comes under 14C. Anti-Allergics in 14. Immunology & Allergy
PK: A: Rapid M: Hepatic E: Urine

Indications & Dose: PERENNIAL/SEASONAL ALLERGIC RHINITIS PO Adult 5-10mg OD, may be increase dose if needed Child 6-12 month: 2.5mg OD, 12 month-2 yr: 2.5mg OD, may increase to 2.5mg q12h, 2-5 yr: 5mg OD, >6 yr: 5-10mg OD Elderly Initially 5mg OD, may increase to 10mg/day | URTICARIA Chronic PO Adult 5-10mg OD, may be increase dose if needed Child 6-12 month: 2.5mg OD, 12 month-2 yr: 2.5mg OD, may increase to 2.5mg q12h, 2-5 yr: 5mg OD, >6 yr: 5-10mg OD Elderly Initially 5mg OD, may increase to 10mg/day

Contra: Hypersensitivity

Precautions: Hepatic impairment, elderly, performing tasks which require mental alertness, Renal impairment (ClCr <11mL/min)

ADR: Others: Headache, somnolence, insomnia, fatigue, malaise, dizziness, abdominal pain, dry mouth, diarrhea, nausea, vomiting, epistaxis, pharyngitis, bronchospasm

DDI: Serious Acenocoumarol anticoagulant effects reduced, Ritonavir increases drug levels, CNS Depressants results in additive CNS depression

Diet: With/without food

Monitor: Relief of symptoms, sedation & anticholinergic effects