Clemastine

Details About Generic Salt ::  Clemastine 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Anti Histamines and Nasal Decongestants

6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM
CLEMASTINE
H1-ANTAGONIST (FIRST GENERATION) | ANTI-ALLERGIC
also comes under 14C. Anti-Allergics in 14. Immunology & Allergy
PK: A: Rapid E: Urine

Indications & Dose: ALLERGIC REACTIONS Prophylactic therapy IV Adult 2mg/day | Acute IV/IM Adult 4mg/day | Prophylactic therapy IM Child 25µg/kg/day in 2 divided doses | HAY FEVER Symptomatic therapy PO Adult 1mg BID, increase up to 6mg/day if needed Child 1–3 yr: 250–500µg BID; 3–6yr: 500µg BID; 6–12 yr: 0.5–1mg BID | URTICARIA Symptomatic therapy PO Adult 1mg BID, increase up to 6mg/day if needed Child 1–3 yr: 250–500µg BID; 3–6yr: 500µg BID; 6–12 yr: 0.5–1mg BID

Contra: Hypersensitivity, narrow-angle glaucoma, CVD, known/suspected prolongation of QT interval, hypokalemia/electrolyte imbalances

Precautions: Urinary retention, prostatic hyperplasia, pyloroduodenal obstruction, epilepsy, hepatic impairment

ADR: Serious: hypotension, tachycardia, hemolytic anemia, thrombocytopenia, agranulocytosis, blurred vision, tinnitus, Others: thickening of bronchial secretions, urinary retention, palpitation, discoordination, sedation, somnolence, sleepiness, confusion, restlessness, nervousness, insomnia, irritability, fatigue, headache, increased dizziness, rash, photosensitivity, diarrhea, nausea, xerostomia, epigastric distress, vomiting, constipation, urinary frequency, difficult urination

DDI: Serious Alcohol impairs co-ordination with high doses of drug

Monitor: Allergic symptoms

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