The Brand Name COLIGYL Has Generic Salt :: Colistin
COLIGYL Is From Company MANKIND Priced :: Rs. 35.99
COLIGYL have Colistin is comes under Sub class #N/A of Main Class #N/A
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
|Colistin||DS D.SYR||Rs. 35.99||30ML|
Indications for Drugs ::
Bowel sterilization, gastrointestinal tract infections, respiratory tract infections
Drug Dose ::
Adult: PO GI infections; Bowel sterilisation 1.5-3 million units 3 times/day. IV/IM GI infections; Bowel sterilisation As colistimethate Na: 6 million units/day in 3 divided doses. Max: 6 million units/24 hr. Inhalation Adjunct to antimicrobial therapy in resp infections As colistimethate Na: 1-2 million units twice daily. Max: 2 million units 3 times/day for up to 3 mth in frequent recurrent infections. Renal impairment: CrCl (ml/min) 20-50 1-2 million units every 8 hr. 10-20 1 million units every 12-18 hr. <10 1 million units every 18-24 hr Contraindication ::
Hypersensitivity. Anuria; porphyria; myasthenia gravis. Pregnancy and lactation.
Drug Precautions ::
Preexisting renal impairment; disorders of neuromuscular transmission. Monitor serum creatinine and BUN regularly while on treatment.
Drug Side Effects ::
Superinfection; renal damage; visual disturbances; GI disturbances, dizziness, nausea, vomiting; confusion, peripheral neuropathy; respiratory insufficiency and muscle weakness. Potentially Fatal: Acute tubular necrosis, neurotoxicity; nephrotoxicity. The neuromuscular blockade is potentially fatal, when associated with use of curariform muscle relaxants.
Pregnancy category ::
Drug Mode of Action ::
Colistin sulfate is a polymyxin antibiotic which is active against aerobic gram-negative bacteria including most enterobacteria except Proteus, Providentia and Serratia. Susceptible organisms include P. aeruginosa, Legionella spp, H. influenzae, Acinetobacter, V. cholera, Salmonella, Shigella and Pasteurella.. Colistin sulfate is used orally while colistimethate sodium is used parenterally or via inhalational route.
Drug Interactions ::
Potentiates chloramphenicol and trimethoprim. Potentially Fatal: Potentiates action of curariform muscle relaxants. Potentiates nephrotoxicity of aminoglycosides and cephalothin.