CRESTOR 7 40MG

The Brand Name CRESTOR Has Generic Salt :: ROSUVASTATIN 

CRESTOR  Is From Company Astrazeneca Priced :: Rs. 364

CRESTOR have ROSUVASTATIN is comes under Sub class Anti Hyperlipidemics of  Main Class Cardiovascular System

Main Medicine Class:: Cardiovascular System  Sub Medicine Class :: Anti Hyperlipidemics 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
ROSUVASTATIN  TAB  Rs. 364  7
Brand Name Company / Manufacturers Strength Unit Price / 7
 CRESTOR  Astrazeneca  40MG  7 Rs. 364

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Astrazeneca :: CRESTOR  ROSUVASTATIN  Cardiovascular System Anti Hyperlipidemics

Indications for Drugs ::

Hyperlipidaemias, Primary hypercholesterolaemia (heterozygous familial hypercholesterolaemia), mixed dyslipidaemia, homozygous familial hypercholesterolaemia, Stroke prevention

Drug Dose ::

Adult: PO: Dose range: 5-40 mg once daily. Initially 5-10 mg once daily increased if necessary at intervals of at least 4 weeks to 20 mg once daily. Daily dose can be increased after further 4 weeks to 40 mg only in severe hypercholesterolaemia with high cardiovascular risk and under specialist supervision. Elderly initially 5 mg once daily. HoFH: Starting dose 20 mg. Child: Heterozygous familial hypercholesterolaemia: >10 yr Initially, 5 mg once daily, may be adjusted at intervals of at least 4 wk. Max: 20 mg once daily. Use 40 mg dose only for patients not reaching LDL-C goal with 20 mg Rosuvastatin can be taken with or without food, at any time of day. Renal impairment: CrCl (ml/min) 30-60 Initially, 5 mg once daily to max 20 mg once daily <30 contraindicated. Contraindication ::

Severe renal impairment, active liver disease, unexplained persistent elevations of serum transaminases; hypersensitivity. Pregnancy, lactation.

Drug Precautions ::

Not to be used in patient with acute, serious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysis e.g. sepsis, hypotension, major surgery, trauma, severe metabolic, endocrine and electrolyte disorders or uncontrolled seizures and combination use with cyclosporine, lopinavir/ritonavir, atazanavir/ritonavir, or certain other lipid-lowering drugs. History of liver disease and alcoholism. Discontinue treatment if there is marked or persistent increase in serum aminotransferase concentrations, significant increase in creatinine phosphokinase or evidence of myopathy.

Drug Side Effects ::

Headache, dizziness, constipation, nausea, vomiting, abdominal pain, myalgia, chest pain, peripheral oedema, depression, insomnia, rash, paraesthesia, proteinuria and asthenia.Potentially Fatal: Rhabdomyolysis with acute renal failure.

Pregnancy category ::
Pregnancy category

5

Drug Mode of Action ::  

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis. It increases the number of hepatic LDL receptors on the cell surface, enhancing uptake and catabolism of LDL. It also decreases apolipoprotein B, triglycerides and increases HDL.

Drug Interactions ::

May increase serum levels of warfarin and oral contraceptives. May increase serum levels w/ itraconazole, HIV protease inhibitors. May decrease serum levels w/ erythromycin and antacids. May increase risk of myopathy w/ fenofibrate, niacin. Potentially Fatal: Increased risk of rhabdomyolysis w/ gemfibrozil and ciclosporin.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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