The Brand Name D-TAIL Has Generic Salt :: Docetaxel
D-TAIL Is From Company Khandelwal Priced :: Rs. 8230
D-TAIL have Docetaxel is comes under Sub class Anti Neoplastic Agents of Main Class Anti Neoplastic Agents
Main Medicine Class:: Anti Neoplastic Agents Sub Medicine Class :: Anti Neoplastic Agents
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
|Docetaxel||INJ||Rs. 8230||1 VIAL|
Indications for Drugs ::
Breast cancer, Lung cancer, Prostate cancer, Stomach cancer, Head/neck cancer
Drug Dose ::
Adult: IV Breast cancer Initial: 60-100 mg/m2 once 3 wkly as a single agent. Gastric adenocarcinoma; Head and neck cancer; Non-small cell lung cancer; Prostate cancer 75 mg/m2 once 3 wkly.
Previous severe hypersensitivity reaction to docetaxel, the solvent or polysorbate 80. Severe neutropenia; pregnancy, severe liver impairment.
Drug Precautions ::
Lactation. Hepatic impairment. Monitor liver blood function and blood counts regularly. Premedication with oral dexamethsaone at 16 mg daily for 3 days, starting one day before docetaxel treatment is recommended.
Drug Side Effects ::
Erythematous patches, eruptions, scleroderma, onycholysis, alopoecia, nausea, vomiting, diarrhoea, stomatitis; increases in hepatic transaminases, bilirubin and alkaline phosphatase; mucositis, asthenia, arthralgia, myalgia, paroxysmal atrial tachycardia, atrial flutter, dysrrhythmia, hypertension and heart failure. Potentially Fatal: Neutropenia; fluid retention syndrome; anaemia.
Pregnancy category ::
Drug Mode of Action ::
Docetaxel disrupts the microtubular network in cells that is essential for vital mitotic and interphase cellular functions. It binds to the free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly, resulting in inhibition of mitosis.
Drug Interactions ::
CYP3A4 inducers, inhibitors, or substrates may alter docetaxel metabolism.