Dextromethorphan

Details About Generic Salt ::  Dextromethorphan 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Anti Tussives,Mucolytics,Expectorants

6C. ANTI-TUSSIVES/MUCOLYTICS/EXPECTORANTS in 6. RESPIRATORY SYSTEM
DEXTROMETHORPHAN
LEVORPHANOL DERIVATIVE | ANTITUSSIVE (NON-NARCOTIC)
PK: A: Rapid M: Liver E: Urine

Indications & Dose: NON-PRODUCTIVE COUGH PO Adult 10-20mg q4h or 30mg q6-8h, max 120mg/day Child 2-6 yr: 2.5-5mg q4h or 7.5mg q6-8h, max 30mg/day, 6-12 yr: 5-10mg q4h or 15mg q6-8h, max 60mg/day

Contra: risk of developing respiratory failure, during acute asthma attack, MAO inhibitor use within past 14 days

Precautions: History of asthma, tartrazine sensitivity, DM, children <2 yrs

ADR: Others: dizziness, GI disturbances, sedation, nausea, vomiting, stomach pain

DDI: Serious Fluoxetine/Amiodarone/Quinidine increases drug level, MAOIs results in hyperpyrexia & coma, SSRIs results in serotonin-like syndrome

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