Dicyclomine

Details About Generic Salt ::  Dicyclomine 

Main Medicine Class:: Gastrointestinal System   Sub Medicine Class ::  Anti Spasmodics

7G. ANTI-SPASMODICS in 7. GASTROINTESTINAL SYSTEM
DICYCLOMINE
ANTI-CHOLINERGIC | ANTISPASMODIC
PK: A: Rapid D: 3.65 L/kg (Vd) E: Urine (80%) & feces (10%)

Indications & Dose: GI SPASM ASSOCIATED WITH IRRITABLE BOWEL SYNDROME PO Adult Initially 10-20mg TID, max 160mg/day Child 6months-2yr: 5-10mg TID/QID 15 min before food; 2-12 yr: 10mg TID | IM Adult 80mg/day in 4 divided doses

Contra: Infants <6 months of age, hypersensitivity, GI/GU tract obstruction, severe UC, reflux esophagitis, unstable cardiovascular status, glaucoma, myasthenia gravis

Precautions: renal/hepatic impairment, autonomic neuropathy, CVD, prostatic hypertrophy, elderly

ADR: Serious: blurred vision, increased IOP, palpitations, paralytic ileus, urinary hesitancy/retention, anaphylaxis, Others: rash, tachycardia, nausea, vomiting, constipation, heartburn, dry mouth, confusion, drowsiness, lightheadedness, psychosis

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