DIP 10 2.5MG

The Brand Name DIP Has Generic Salt :: Amlodipine 

DIP  Is From Company Pentacare Priced :: Rs. 14.5

DIP have Amlodipine is comes under Sub class Anti Anginals of  Main Class Cardiovascular System

Main Medicine Class:: Cardiovascular System  Sub Medicine Class :: Anti Anginals 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Amlodipine  TAB  Rs. 14.5  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 DIP  Pentacare  2.5MG  10 Rs. 14.5

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Pentacare :: DIP  Amlodipine  Cardiovascular System Anti Anginals

Indications for Drugs ::

Mild to moderate hypertension, Chronic stable and vasospastic angina, Raynaud’s disease, Coronary Artery Disease, HTN, Stroke prevention

Drug Dose ::

Adult: PO Stable angina; HTN; Prinzmetal’s angina Initial: 5 mg once daily; If the desired therapeutic effect cannot be achieved within 2-4 weeks, the dose may be increased to a maximum dose of 10 mg once daily. Child: >12 yr Initially, 2.5 mg once daily, increased to 5 mg once daily if necessary. Elderly: Initially, 2.5 mg once daily. Hepatic impairment: Initially, 2.5 mg once daily.

Contraindication ::

Hypersensitivity to Amlodipine or other calcium channel antagonist, Severe hypertension.

Drug Precautions ::

Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution when used in patients with idiopathic hypertrophic subaortic stenosis. Elderly, children. Pregnancy, lactation. Use in renal failure: Although Amlodipine is excreted primarily via kidney, mild renal impairment does not appear to have an effect on the plasma concentrations. Severe renal impairment may however require a dosage reduction. Amlodipine is not dialyzable. Use in patients with impaired hepatic function: Amlodipine half-life is prolonged in patient with impaired hepatic function. Amlodipine should therefore be administered at lower (5mg) initial dose in these patients. Use in heart failure: An increased number of pulmonary oedema has been reported.

Drug Side Effects ::

Headache, peripheral oedema, fatigue, somnolence, nausea, abdominal pain, flushing, dyspepsia, palpitations, dizziness. Rarely pruritus, rash, dyspnoea, asthenia, muscle cramps.Potentially Fatal: Hypotension, bradycardia, conductive system delay and CCF.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.

Drug Interactions ::

Plasma concentrations may be elevated w/ CYP3A4 inhibitors (e.g. azole antifungals, ritonavir). Concomitant therapy w/ simvastatin may increase risk of myopathy including rhabdomyolysis. May increase ciclosporin plasma levels and conivaptan.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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