Article Contents ::
Details About Generic Salt :: Doxylamine , Pyridoxine
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 7D. ANTI-EMETICS in 7. GASTROINTESTINAL SYSTEM |
| DOXYLAMINE + PYRIDOXINE |
| H1 ANTAGONIST & VITAMIN(WATER SOLUBLE) | ANTI-EMETIC |
| PK: A: Well absorbed D: 2.5L/kg (Vd) M: Hepatic E: Urine |
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Indications & Dose: PREGNANCY ASSOCIATED WITH NAUSEA & VOMITING PO Adult 2 tab HS (each tablet consists of doxylamine 10mg & pyridoxine 10mg), in severe cases dose may be increased by 1 tablet in morning & afternoon |
| Contra: Hypersensitivity
Precautions: Angle-closure glaucoma, CVD, hyperthyroidism, urinary tract obstruction, history of increased IOP ADR: Serious: palpitations, tachycardia, blurred vision, Others: anorexia, diarrhea, dizziness, drowsiness, vertigo, disorientation, dysuria, diplopia, constipation, drymouth DDI: Serious Amphetamine decreases drug levels, Barbiturates/ACEIs effects are decreases, CNS Depressants/Alcohol effects are increases, Droperidol increases drug effects |
