The Brand Name ENDOPACE Has Generic Salt :: Domperidone 

ENDOPACE  Is From Company Themis Priced :: Rs. 19.86

ENDOPACE have Domperidone is comes under Sub class Anti Emetics of  Main Class Gastrointestinal System

Main Medicine Class:: Gastrointestinal System  Sub Medicine Class :: Anti Emetics 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Domperidone  SUS  Rs. 19.86  60ML
Brand Name Company / Manufacturers Strength Unit Price / 60ML
 ENDOPACE  Themis  1MG/ML  60ML Rs. 19.86

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Themis :: ENDOPACE  Domperidone  Gastrointestinal System Anti Emetics

Indications for Drugs ::

Gastritis, Lactation, Migraine, Nausea and vomiting, Gastroparesis, Non ulcer dyspepsia

Drug Dose ::

Adults : 10 – 20 mg every 4 – 8 hours daily Children : 0.2 – 0.4 mg/kg every 4 – 8 hours daily. Nausea and vomiting 10-20 mg 4-8 hrly. Max: 80 mg/day. Non ulcer dyspepsia 10-20 mg 3 times/day and at night. Migraine 20 mg 4 hrly. Max: 4 doses/24 hr. Rectal: Nausea and vomiting 60 mg twice daily.

Contraindication ::

Hypersensitivity. GI haemorrhage, obstruction and perforation, patients with prolactin releasing pituitary hormone, chronic admin or routine prophylaxis of postoperative nausea and vomiting.

Drug Precautions ::

Phaeochromocytoma; children<2 yr, elderly; renal or hepatic impairment. Risk of cardiac arrhythmias and hypokalaemia if administered IV. Pregnancy and lactation. Drug Side Effects ::

Drowsiness, extrapyramidal reactions, galactorrhoea, gynaecomastia; constipation or diarrhoea, lassitude, decreased libido, skin rash, itch. Potentially Fatal: Convulsions, arrhythmias and cardiac arrest, dysrrhythmias in patients with CV disease or hypokalaemia, patients on cancer chemotherapy. Seizures; hypertensive crisis in patients with phaeochromocytoma.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Domperidone is a peripheral dopamine-receptor blocker. It increases oesophageal peristalsis, enhances gastroduodenal coordination and lowers oesophageal sphincter pressure, gastric motility and peristalsis, thus facilitating gastric emptying and decreasing small bowel transit time.

Drug Interactions ::

May antagonise the hypoprolactinaemic effect of bromocriptine. May antagonise the prokinetic effect w/ opioid analgesics and antimuscarinics. Potentially Fatal: Potent CYP3A4 inhibitors (e.g. ketoconazole, erythromycin or ritonavir) may increase serum domperidone levels and subsequently increasing the risk of QT prolongation.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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