Ethionamide

Details About Generic Salt ::  Ethionamide 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Drugs for Tuberculosis

13O. DRUGS FOR TUBERCULOSIS in 13. ANTI-INFECTIVES
ETHIONAMIDE
THIOAMIDE DERIVATIVE | ANTI-TB & ANTI-LEPROSY
also comes under 13P. Anti-Leprotics in 13. Anti-Infectives
PK: A: Rapid D: Extensively M: Hepatic E: Urine

Indications & Dose: LEPROSY PO Adult 15-20mg/kg/day, max 1g/day Child 15-20mg/kg/day, max 1g/day in 2-3 divided doses | TUBERCULOSIS PO Adult 15-20mg/kg/day, max 1g/day Child 15-20mg/kg/day, max 1g/day in 2-3 divided doses

Contra: Hypersensitivity

Precautions: Renal/hepatic impairment, history of psychiatric illness, DM, porphyria

ADR: Serious: hepatitis, thrombocytopenia, hypoglycemia, hypothyroidism, postural hypotension, Others: diarrhea, nausea, vomiting, stomatitis, abdominal pain, alopecia, dermatitis, anxiety, depression, dizziness, drowsiness

DDI: Serious Cycloserine leads to neurotoxic adverse effects, Isoniazid results in acute psychotic reactions

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