Details About Generic Salt ::  Exemestane 

Main Medicine Class:: Anti Neoplastic Agents   Sub Medicine Class ::  Anti Neoplastic Agents

18A. ANTI-NEOPLASTIC AGENTS in 18. ANTI-NEOPLASTIC AGENTS
EXEMESTANE
AROMATASE INHIBITOR | HORMONAL ANTI-NEOPLASTIC
PK: A: Rapid & moderate (PO) D: Extensive into tissues M: Hepatic E: Urine (<1% as unchanged drug, 39%-45% as metabolites), feces (36%-48%)

Indications & Dose: ADVANCED BREAST CANCER PO Adult Females postmenopausal 25mg/day continued until tumor progression | EARLY BREAST CANCER Adjuvant therapy PO Adult 25mg OD (following 2-3 yr of tamoxifen therapy) for 5 yr of endocrine therapy (in the absence of recurrence of contralateral breast cancer)

Contra: hypersensitivity, premenopausal women, suspected pregnancy

Precautions: concurrent use of estrogen-containing drugs, double the dose (50mg) in patients treated with rifampicin/phenytoin

ADR: Serious: arthralgia, MI, angina, osteoarthritis, osteoporosis, carpal tunnel syndrome, thromboembolism, HTN, Others: UTI, hyperhidrosis, alopecia, fatigue, insomnia, headache, depression, hot flashes, nausea, abdominal pain, visual disturbances, dermatitis, itching, rash, weight gain, diarrhea, constipation, anorexia, appetite increased, dyspnea, cough, bronchitis, pharyngitis, sinusitis, URTI, flu-like syndrome, lymphedema, infect

DDI: Serious Phenobarbital/Carbamazepine/Phenytoin reduces drug level

Diet: After food

DOWNLOAD OUR ANDROID APP

One of the 1st in India.High Quality Generic Medicine Portal Android Application for Online Oreder & Information.

For More Join Our Membership and Get Additional 25% off on Meds, also get MLM Benefits to get a permanent earning source.

Join Membership How to Search Medicine
Android App

We would like to keep you updated with special notifications.