Flunarizine

Details About Generic Salt ::  Flunarizine 

Main Medicine Class:: Nervous System   Sub Medicine Class ::  Anti Migraine , Anti Vertigo Drugs

1H. ANTI-MIGRAINE & ANTI- VERTIGO DRUGS in 1. NERVOUS SYSTEM
FLUNARIZINE
H1-RECEPTOR BLOCKER & CCB | ANTI-MIGRAINE
PK: A: Well absorbed D: 43.2L/kg (Vd) M: Hepatic E: Urine

Indications & Dose: MIGRAINE Prophylactic therapy PO Adult 5-10mg/day HS | PERIPHERAL & CEREBRAL VASCULAR DISORDERS PO Adult 5-10mg/day HS | VERTIGO PO Adult 5-10mg/day HS | VESTIBULAR DISORDERS PO Adult 5-10mg/day HS

Contra: Hypersensitivity, depression, parkinson’s disease, extrapyramidal disorders, porphyria

Precautions: Elderly, fatigue, driving/operating machinery, angle-closure glaucoma, urinary retention, prostatic hyperplasia, pyloroduodenal obstruction, epilepsy, severe hepatic impairment

ADR: Serious: increased prolactin level, Others: increased appetite, nausea, vomiting, xerostomia, weight gain, heart burn, Anxiety, dizziness, drowsiness, fatigue, insomnia, rash, galactorrhea

DDI: Serious Phenytoin/Carbamazepine/Valproic acid reduces drug level

Monitor: EPS, fatigue

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