Flurazepam

Details About Generic Salt ::  Flurazepam 

Main Medicine Class:: Nervous System   Sub Medicine Class ::  Sedatives , Hypnotics

1A. SEDATIVES & HYPNOTICS in 1. NERVOUS SYSTEM
FLURAZEPAM
LONG-ACTING BENZODIAZEPINE | SEDATIVE, HYPNOTIC
PK: A: Rapid D: 3.4L/kg (Vd) M: Hepatic E: Urine

Indications & Dose: INSOMNIA Short-term therapy PO Adult 15–30mg HS <4wk Child <15 yrs: Dose not established, >15 yrs: 15mg HS Elderly 15mg HS

Contra: hypersensitivity to flurazepam/other benzodiazepines, preexisting CNS depression, angle-closure glaucoma

Precautions: hepatic impairment, history of suicide attempt, drug dependence, elderly, children <15 yrs

ADR: Serious: Blurred vision, depression, Others: dizziness, daytime drowsiness, headache, confusion, paradoxical excitation, ataxia, nausea, vomiting, diarrhea, constipation, abdominal pain, sleep apnea, rash, abnormal taste, physical/ psychological drug dependence

DDI: Serious Clozapine causes severe hypotension, respiratory depression or loss of consciousness, HIV protease inhibitors increases drug bioavailability, Cimetidine increases drug level, Alcohol increases risk of drowsiness, impaired performance & driving skills

Diet:

Monitor: Mental status, CBC, LFTs, kidney function tests

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