Folic acid

Details About Generic Salt ::  Folic acid 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

20A. VITAMINS & MINERALS in 20. VITAMINS, MINERALS AND COMBINATIONS
FOLIC ACID
WATER SOLUBLE VITAMIN | SUPPLEMENT
PK: A: Rapid M: Hepatic E: Urine

Indications & Dose: FIRST OCCURRENCE OF NEURAL TUBE DEFECTS Prophylactic therapy PO Adult 400-500µg/day before conception & during the first 12wk of pregnancy | FOLATE-DEFICIENCY ANEMIA/MEGALOBLASTIC ANEMIA PO Adult 5mg/day 4 months (in pregnancy continued to term), may be increased to 15mg/day in case of malabsorption | RECURRENCE OF NEURAL TUBE DEFECTS Prophylactic therapy PO Adult 5mg/day 4 wk before conception until 12th week of pregnancy

Contra: Hypersensitivity, undiagnosed megaloblastic anemia, pernicious, aplastic, normocytic anemia

Precautions: Deficiencies of other vitamins, alcoholism, hematopoiesis, neonates

ADR: Serious: bronchospasm, flushing, Others: Allergic reactions, erythema, malaise, pruritus, rash

DDI: Serious Phenytoin levels reduced, Sulfasalazine/Antacids reduces drug absorption, Methotrexate/AntiConvulsants/Phenobarbital/Primidone reduces drug levels, Fluorouracil toxicity raises

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