Fosinopril

Details About Generic Salt ::  Fosinopril 

Main Medicine Class:: Cardiovascular System   Sub Medicine Class ::  Anti Hypertensives

4D. ANTI-HYPERTENSIVES in 4. CARDIOVASCULAR SYSTEM
FOSINOPRIL
ACEI | ANTI-HYPERTENSIVE
also comes under 4A. Drugs for Cardiac Failure & Shock in 4. Cardiovascular System
PK: A: Well absorbed M: hepatic, intestine E: Urine, feces

Indications & Dose: HEART FAILURE PO Adult Initially 10mg/day & increase as needed, max 40mg OD over several wk usual dose 20-40mg/day | HYPERTENSION PO Adult Initially 10mg/day MD 20-40mg/day max 80mg/day Child >6 yr (>50kg): Initially 5-10mg/day max 40mg/day

Contra: Hypersensitivity, angioedema related to previous treatment with an ACE inhibitor

Precautions: Aortic stenosis, collagen vascular disease, CVD, hypertrophic cardiomyopathy, renal artery stenosis, renal impairment, before, during/immediately after major surgery

ADR: Serious: Orthostatic hypotension, palpitation, Others: musculoskeletal pain, dizziness, diarrhea, nausea, vomiting, transaminases increased, weakness, cough, URTI

DDI: Serious Antacids reduce drug bioavailability

Diet:

Monitor: BP, Se Cr & K, CBC

Related Posts:
You May Also Like::
Tagged with