Galantamine

Details About Generic Salt ::  Galantamine 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

1F. DRUGS FOR NEURODEGENERATIVE DISORDERS in 1. NERVOUS SYSTEM
GALANTAMINE
CHOLINESTERASE INHIBITOR | ANTI-ALZHEIMER
PK: A: Rapid & complete D: 175 L M: Hepatic E: Urine

Indications & Dose: ALZHEIMER’S DISEASE PO Adult Initially 4mg BID 4 wk, then increase to 8mg BID 4 wk, may be increase to 12mg BID according to response and tolerance

Contra: Hypersensitivity, severe renal/hepatic dysfunction

Precautions: Respiratory disease, PUD, cardiac conduction abnormalities, seizures, urinary tract obstruction, mild-to-moderate hepatic impairment, moderate renal impairment

ADR: Serious: Bradycardia, syncope, tremor, rhinitis, Others: anemia, nausea, vomiting, anorexia, diarrhea, weight loss, abdominal pain, dyspepsia, flatulence, hematuria, dizziness, headache, depression, insomnia

DDI: Serious Atropine causes antagonistic effects, Ketoconazole/Fluoxetine/Paroxetine/Quinidine increases drug level, β-blockers increases risk of bradycardia, Diltiazem/Amiodarone/Verapamil leads to bradycardia

Diet: With food

Monitor: Mental status

Related Posts:
You May Also Like::