Gliclazide

Details About Generic Salt ::  Gliclazide 

Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System   Sub Medicine Class ::  Insulin , Anti Diabetic drugs

8D. INSULIN & ANTI-DIABETIC DRUGS in 8. ENDOCRINE/STEROID HORMONES & METABOLIC SYSTEM
GLICLAZIDE
SULFONYLUREA | ANTI-DIABETIC
PK: A: Rapid M: Hepatic E: Urine(60% to 70%) & feces (10% to 20%)

Indications & Dose: TYPE 2 DIABETES MELLITUS PO Adult IR tablet: Initially 80-160mg/day, doses >160mg/day should be given in 2 equal divided doses, max 320mg/day, SR tablet: 30-120mg/day

Contra: Hypersensitivity, type 1 DM, DKA

Precautions: Elderly, hepatic/renal impairment

ADR: Serious: Hypoglycemia, jaundice, thrombocytopenia, hepatitis, Others: dizziness, headache, anorexia, constipation, diarrhea, epigastric fullness, nausea, paresthesia, myalgia

DDI: Serious Rifampicin reduces drug effects, Fluconazole/Disopyramide/Miconazole results in hypoglycemia

Diet: With food

Monitor: Blood glucose & Hb A1c

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