Glimepiride

Details About Generic Salt ::  Glimepiride 

Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System   Sub Medicine Class ::  Insulin , Anti Diabetic drugs

8D. INSULIN & ANTI-DIABETIC DRUGS in 8. ENDOCRINE/STEROID HORMONES & METABOLIC SYSTEM
GLIMEPIRIDE
SULPHONYLUREA | ANTI-DIABETIC
PK: A: Rapid D: 8.8L (Vd) M: Hepatic E: Urine(60%) & feces(40%)

Indications & Dose: TYPE 2 DIABETES MELLITUS PO Adult Initially 1-2mg OD, increase by 2mg at 1–2 wk intervals based on response, MD 1-4mg OD max 8mg OD

Contra: Hypersensitivity, DKA

Precautions: Elderly, hepatic/renal impairment

ADR: Serious: Hypoglycemia, hyponatremia, thrombocytopenia, hepatitis, Others: dizziness, headache, anorexia, constipation, diarrhea, epigastric fullness, nausea, paresthesia, myalgia

DDI: Serious Fluvoxamine/Fluconazole increases drug level, Rifampicin reduces drug level, Gatifloxacin results in hypoglycemia

Diet: With food

Monitor: Hypoglycemia, blood glucose,HbA1c

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