The Brand Name GLYNASE (SEMI) Has Generic Salt :: Glipizide
GLYNASE (SEMI) Is From Company U S V Priced :: Rs. 5.35/9.04
GLYNASE (SEMI) have Glipizide is comes under Sub class Insulin , Anti Diabetic drugs of Main Class Endocrine,Steroid Hormones , Metabolic System
Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System Sub Medicine Class :: Insulin , Anti Diabetic drugs
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Indications for Drugs ::
Type 2 DM
Drug Dose ::
Adult: PO Initial: 2.5-5 mg/day as a single dose, may increase slowly. Doses >15 mg may be given in 2 divided doses. Max: 40 mg/day. Hepatic impairment: Severe: Contraindicated.
Hypersensitivity. Type 1 DM; ketoacidosis; severe renal or hepatic insufficiency. Pregnancy, lactation.
Drug Precautions ::
Hypoglycaemia, stress, elderly. Thyroid impairment; moderate hepatic or renal impairment. Monitor blood glucose concentration.
Drug Side Effects ::
GI upsets, diarrhoea, nausea; allergic skin reactions, leucopenia, thrombocytopenia, agranulocytosis, hyponatraemia; jaundice; haemolytic anaemia, pancytopenia. Potentially Fatal: Hypoglycaemia in presence of renal or hepatic damage and alcohol.
Pregnancy category ::
Drug Mode of Action ::
Drug Interactions ::
Increased plasma concentration w/ certain antifungals (e.g. miconazole, fluconazole). Protein-bound drugs (e.g. NSAIDs, other sulfonamides, oral anticoagulants, hydantoins), probenecid, MAOIs, and chloramphenicol may potentiate hypoglycaemic action of glipizide. Diminished therapeutic effect w/ thiazides, other diuretics, phenothiazines, thyroid agents, oestrogens, OC, phenytoin, nicotinic acid, sympathomimetics, Ca channel blockers, rifampicin and isoniazid. Concomitant use w/ ?-blockers may impair glucose tolerance, increase frequency or severity of hypoglycaemia and block hypoglycaemia-induced tachycardia. Decreased serum concentration w/ colesevelam.