Ivermectin

Details About Generic Salt ::  Ivermectin 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Anthelmintics

13L. ANTHELMINTICS in 13. ANTI-INFECTIVES
IVERMECTIN
AVERMECTINS DERIVATIVE (SEMISYNTHETIC) | ANTHELMINTIC
PK: A: Well absorbed D: 3-3.5 L/kg (Vd) M: Hepatic E: Feces, urine

Indications & Dose: ONCHOCERCIASIS PO Adult 150µg/kg single dose, retreatment may be required q3-12 month until asymptomatic Child >15 kg: Same as adult dose | STRONGYLOIDIASIS PO Adult 200µg/kg single dose or 2 days Child >15 kg: Same as adult dose

Contra: Hypersensitivity

ADR: Serious: arthralgia, myalgia, lymphadenopathy, tachycardia, Others: Ocular irritation, somnolence, raised liver enzymes, postural hypotension, mazzotti reaction, fever, headache, cough, pruritus, rash, conjunctivitis, lymphadenitis, nausea, vomiting, diarrhea

DDI: Serious Levamisole/Alcohol increase drug bioavailability

Diet: Empty stomach

Monitor: Skin, eye microfilarial counts, periodic ophthalmologic exams, stool examinations