The Brand Name LIPEZET Has Generic Salt :: EZETIMIBE
LIPEZET Is From Company Piramal Hc. Priced :: Rs. 79
LIPEZET have EZETIMIBE is comes under Sub class Anti Hyperlipidemics of Main Class Cardiovascular System
Main Medicine Class:: Cardiovascular System Sub Medicine Class :: Anti Hyperlipidemics
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Indications for Drugs ::
Hyperlipidaemias, Homozygous familial sitosterolaemia, Hypercholesterolaemia
Drug Dose ::
Adult: PO Homozygous familial sitosterolaemia; Hyperlipidaemias 10 mg once daily.
Hypersensitivity; moderate to severe liver disease or unexplained serum transaminase elevation. Children <10 yr, lactation. Drug Precautions ::
Renal or mild hepatic impairment. Monitor LFTs. Immediately discontinue ezetimibe and any HMG-CoA reductase inhibitor or fibrate if myopathy is diagnosed or suspected. Exclude or treat secondary causes of dyslipidaemia prior to initiating therapy.
Drug Side Effects ::
Abdominal discomfort, headache, dizziness, sinusitis, pharyngitis; diarrhoea, chest pain, arthralgia, myalgia, resp infection and fatigue.
Pregnancy category ::
Drug Mode of Action ::
Ezetimibe localises at the brush border of the small intestine where it inhibits the absorption of cholesterol, thus decreasing its delivery to the liver. This results in decrease in cholesterol stores within the liver and an increase in cholesterol clearance from the blood.
Drug Interactions ::
Reduced absorption w/ colestyramine. Increased plasma concentrations w/ ciclosporin. Concomitant use w/ oral anticoagulants may result in increased INR.