Lomefloxacin

Details About Generic Salt ::  Lomefloxacin 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Quinolones

13G. QUINOLONES in 13. ANTI-INFECTIVES
LOMEFLOXACIN
FLUOROQUINOLONE | ANTI-INFECTIVE
also comes under 3C. Anti-Infectives in 3. Ocular
PK: A: Rapid & complete D: Extensive M: Hepatic E: Urine, feces

Indications & Dose: BACTERIALCONJUNCTIVITIS TP Adult Instill 0.3% solution into affected eye | CYSTITIS Acute/Uncomplicated PO Adult 400mg OD 3days in women | SURGICAL INFECT Prophylactic therapy PO Adult 400mg single dose 1-6 h before the procedure | SUSCEPTIBLE INFECT PO Adult 400mg OD 10-14 daysincludes bronchitis due to Haemophilus influenzae or Moraxella catarrhalis

Contra: Hypersensitivity

Precautions: Patients with epilepsy/ history of CNS disorders, renal impairment, G6PD deficiency, myasthenia gravis, tendon damage, QT prolongation, electrolyte disturbances, bradycardia, pre-existing cardiac disease, avoid exposure to strong sunlight/sunlamps

ADR: Serious: Pseudomembranous colitis, pancreatitis, hallucinations, psychotic reactions, depression, convulsions, hepatitis, eosinophilia, paresthesia, peripheral neuropathy, vasculitis, SJS, TEN, photosensitivity, ventricular arrhythmias, ARF, prolongation of QT interval, Others: nausea, vomiting, diarrhea, abdominal pain, dysphagia, dyspepsia, headache, dizziness, drowsiness, rash

DDI: Serious Ferrous Sulphate/Antacids/Sucralfate reduces drug absorption

Diet: 2h after food

Monitor: CBC, renal & hepatic function (prolonged therapy)

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