The Brand Name MELWIN Has Generic Salt :: Meloxicam
MELWIN Is From Company Genix Ph. Priced :: Rs. 10.00/18.00
MELWIN have Meloxicam is comes under Sub class Analgesics , Anti inflammatory Drugs of Main Class Musculoskeletal Disorders , Pain
Main Medicine Class:: Musculoskeletal Disorders , Pain Sub Medicine Class :: Analgesics , Anti inflammatory Drugs
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Indications for Drugs ::
Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis
Drug Dose ::
Rheumatoid arthritis Adult: 15 mg daily as a single dose. Patients with increased risk of adverse effects: Initially 7.5 mg. Elderly: 7.5 mg daily for long-term treatment. Ankylosing spondylitis Adult: 15 mg daily as a single dose. Patients with increased risk of adverse effects: Initially 7.5 mg. Elderly: 7.5 mg daily for long-term treatment. Acute exacerbations of osteoarthritis Adult: 7.5 mg daily up to a max of 15 mg as a single dose. Elderly: 7.5 mg daily. Juvenile rheumatoid arthritis Child: >2 yr: 125 mcg/kg ocne daily. Max dose: 7.5 mg daily.
Hypersensitivity to meloxicam, aspirin or other NSAIDs; severe hepatic impairment; bleeding disorders; renal failure without dialysis. Rectal admin in patients with proctitis, haemorrhoids or rectal bleeding.
Drug Precautions ::
History of GI disease, asthma, hypertension, CVD or risk factors, fluid retention or heart failure. Monitor patients with advanced renal disease. May impair ability to drive or operate machinery. Elderly. Pregnancy (avoid in the 3rd trimester) and lactation.
Drug Side Effects ::
Dyspepsia, headache, nausea, diarrhoea, upper respiratory tract infection, abdominal pain, dizziness, oedema, flatulence, influenza-like symptoms, back pain, muscle spasms, musculoskeletal pain, rash, anaemia. GI perforation, ulceration and/or bleeding. In children: Abdominal pain, vomiting, diarrhoea, headache, pyrexia. Potentially Fatal: Stevens Johnson syndrome, thrombocytopenia, interstitial nephritis and idiosyncratic liver abnormality.
Pregnancy category ::
Drug Mode of Action ::
Meloxicam is an oxicam derivative which exhibits analgesic, antipyretic and anti-inflammatory actions. It reversibly inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors.
Drug Interactions ::
Increased risk of severe GI effects w/ aspirin or warfarin. May antagonise antihypertensive effects of ACE inhibitors and angiotensin II receptor antagonists. May reduce natriuretic effects of furosemide and thiazides. Enhanced toxicity of methotrexate. May increase plasma lithium concentration.