Mianserin

Details About Generic Salt ::  Mianserin 

Main Medicine Class:: Nervous System   Sub Medicine Class ::  Anti Depressants

1D. ANTI-DEPRESSANTS in 1. NERVOUS SYSTEM
MIANSERIN
TETRACYCLIC DERIVATIVE | ANTI-DEPRESSANT
PK: A: Rapid D: Extensive M: Hepatic E: Urine

Indications & Dose: DEPRESSION PO Adult Initially 30-40mg/day, may be increased according to response MD 30-90mg/day as single dose HS max 200mg Elderly Initially 30mg/day increased if needed

Contra: Porphyria

Precautions: CVD, DM, renal/hepatic impairment, epilepsy, prostatic hyperplasia, angle-closure glaucoma

ADR: Serious: bone-marrow depression, gynecomastia, liver dysfunction, polyarthropathy, blood disorders, Others: drowsiness, erythema multiforme

DDI: Serious Ephedrine action reduces, Alcohol causes drowsiness & impair ability to drive/handle dangerous machinery, Acenocoumarol efficacy decreases, Warfarin efficacy increases, Phenytoin/Carbamazepine reduces drug level

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