The Brand Name MINDOL Has Generic Salt :: Haloperidol
MINDOL Is From Company Synapse Priced :: Rs. 4.5
MINDOL have Haloperidol is comes under Sub class Anti Psychotics of Main Class Nervous System
Main Medicine Class:: Nervous System Sub Medicine Class :: Anti Psychotics
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Indications for Drugs ::
Schizophrenia, Delirium, Hiccups, Acute psychosis, Hyperactivity, Aggression, Agitation and confusion, Tic disorders, Tourette syndrome, Chorea, Nausea and vomiting, Dementia.
Drug Dose ::
Adult: PO Psychoses 0.5-5 mg 2-3 times/day, up to 100 mg/day in severe cases. Maintenance: 3-10 mg/day. Severe tics; Tourette’s syndrome Initial: 0.5-1.5 mg 3 times/day, up to 10 mg/day in Tourette’s syndrome. Adjunct in severe anxiety or behavioral disturbances 0.5 mg twice daily. Restlessness and confusion 1-3 mg 8 hrly. Intractable hiccup 1.5 mg 3 times/day. Intramuscular: Acute psychosis 2-10 mg hrly or 4-8 hrly until symptoms are controlled. Max: 18 mg/day. Nausea and vomiting 0.5-2 mg/day.
Severe toxic CNS depression; preexisting coma; Parkinson’s disease; lactation.
Drug Precautions ::
Parkinsonism; epilepsy, allergy, angle-closure glaucoma, benign prostatic hyperplasia; severe cardiac or hepatic disease; extremes in temp (hot and cold weather); presence of acute infections or leucopenia; hyperthyroidism; pregnancy, elderly, children. Patients receiving anticoagulants. Discontinue upon signs of neurological toxicity in patients taking haloperidol and lithium.
Drug Side Effects ::
Tardive dyskinesia; extrapyramidal reactions. Anxiety, drowsiness, depression, anorexia, transient tachycardia, postural hypotension, leukopenia; anticholinergic side effects.Potentially Fatal: Neuroleptic malignant syndrome
Pregnancy category ::
Drug Mode of Action ::
Haloperidol blocks postsynaptic dopamine D1 and D2 receptors in the mesolimbic system and decreases the release of hypothalamic and hypophyseal hormones. It produces calmness and reduces aggressiveness with disappearance of hallucinations and delusions.
Drug Interactions ::
Carbamazepine and rifampicin reduce plasma concentrations. Symptoms of CNS depression may be enhanced by CNS depressants e.g. alcohol, hypnotics, general anaesthetics, anxiolytics and opioids. May reduce antihypertensive action of guanethidine. May increase risk of arrhythmia when used with drugs that prolong QT interval or diuretics that can cause electrolyte imbalance. May increase plasma levels of haloperidol when used with clozapine or chlorpromazine. Potentially Fatal: Increases lithium blood levels and may predispose to neuroleptic malignant syndrome.