Mometasone

Details About Generic Salt ::  Mometasone 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Drugs For Asthma,COPD,ARDS

6A. DRUGS FOR ASTHMA/COPD/ARDS in 6. RESPIRATORY SYSTEM
MOMETASONE
CORTICOSTEROID | ANTI-ALLERGIC, ANTI-ASTHMATIC
also comes under 2B. Corticosteroids in 2. Ear, Nose & Throat (ENT),  ,   15A. Corticosteroids (Topical) in 15. Skin

Indications & Dose: ASTHMA Mild-to-moderate Prophylactic therapy Inh Adult Dry powder: Initially 400µg OD, MD 200µg OD/BID Child 12-18 yr: 200-400µg as single dose/ in 2 divided doses, increased to 400µg BID if needed | CORTICOSTEROID RESPONSIVE DERMATOSES TP Adult Lotion: Apply few drops to affected area OD, Cream/ointment: Apply thin film to affected area OD Child Lotion: >12 yr same as adult dose, Cream/ointment:>2 yr: Same as adult dose | NASAL POLYPS NSL Adult 100µg (2 sprays) in each nostrils BID, total daily dose 400µg | SEASONAL ALLERGIC RHINITIS Prophylactic therapy NSL Adult 200µg/day (2 sprays in each nostrils) initiated 2-4 wks prior to start of pollen season Child >12 yrs: Same as adult dose | SEASONAL/PERENNIAL ALLERGIC RHINITIS Symptomatic therapy NSL Adult 100µg (2 sprays) in each nostril daily, total daily dose 100µg Child 2-11 yr: 50µg (1 sprays) in each nostril daily, total daily dose 100µg, >12 yr: Same as adult dose

Contra: Hypersensitivity to drug, intolerance of alcohol/bisulfites/tartrazine, active untreated infect, hypersensitivity to milk proteins, primary treatment of status asthmaticus, acute bronchospasm

Precautions: HTN, osteoporosis, DM, glaucoma, immunosuppression, seizure disorders, renal disease, hypothyroidism, cirrhosis, diverticulitis, active/latent PUD, IBD, UC, thromboembolic disorder/tendency, myasthenia gravis, HF, metastatic cancer, emotional instability, recent GI surgery, children <6 yr

ADR: Serious: Increased ICP, seizures, HF, thrombophlebitis, thromboembolism, fat embolism, arrhythmias, shock, adrenal suppression, hypothalamic-pituitary adrenal suppression, bronchospasm, hypotension/HTN, glaucoma, increased IOP, throat irritation, pancreatitis, cushingoid state, sodium & fluid retention, hypercholesterolemia, tendon rupture, osteoporosis, nasopharyngeal/oropharyngeal fungal infect, immunosuppression, hypersensitivity reaction, Others: hoarseness, rash, acne, hirsutism, thin & fragile skin, petechiae, weight gain, muscle wasting, myopathy, dry mouth, anorexia, amenorrhea/irregular menses, nausea, vomiting, abdominal distention, esophageal candidiasis/ulcer, nasal congestion & irritation, Churg-Strauss syndrome, headache, nervousness, restlessness, personality changes, vertigo, euphoria, paresthesia, insomnia

DDI: Serious Antidiabetics effects/levels decreases by drug, HIV protease inhibitors/Azoles increases levels/effects of drug, Loop diuretics/Amphotericin-B/Thiazides levels/effects increases by drug

Monitor: ECG, blood glucose & electrolyte levels, urinalysis, LFT, cushing’s syndrome, RFT

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