Nabumetone

Details About Generic Salt ::  Nabumetone 

Main Medicine Class:: Musculoskeletal Disorders , Pain   Sub Medicine Class ::  Analgesics , Anti inflammatory Drugs

12E. ANALGESICS & ANTI-INFLAMMATORY DRUGS in 12. MUSCULOSKELETAL DISORDERS & PAIN
NABUMETONE
NSAID | ANTI-ARTHRITIC
PK: A: Well absorbed M: Hepatic E: Urine (80%) & feces (9%)

Indications & Dose: OSTEOARTHRITIS Symptomatic therapy PO Adult 1g OD as single dose or in 2 divided doses MD 1-2g/day | RHEUMATOID ARTHRITIS Symptomatic therapy PO Adult 1g/day MD 1-2g/day as single or in 2 divided doses

Contra: Hypersensitivity, severe hepatic impairment, perioperative pain CABG surgery, active PUD, severe HF, children with varicella, history of hypersensitivity reactions

Precautions: Severe CVD/renal disease, history of ulcer disease, children, HTN, patients with infect, patients with hemorrhagic disorders, elderly

ADR: Serious: GI bleeding, angioedema, anaphylaxis, tinnitus, edema, Others: nausea, vomiting, diarrhea, constipation, abdominal pain, dyspepsia, dry mouth, pruritus, rash, dizziness, drowsiness, fatigue, headache, insomnia, vasculitis, abnormal vision

Diet: With food

Monitor: Patients with renal insufficiency: Baseline renal function followed by repeat test within weeks

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