Nandrolone

Details About Generic Salt ::  Nandrolone 

Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System   Sub Medicine Class ::  Anabolic Steroids

8C. ANABOLIC STEROIDS in 8. ENDOCRINE/STEROID HORMONES & METABOLIC SYSTEM
NANDROLONE
ANDROGEN | ANABOLIC STEROID
PK: M: Hepatic E: Urine

Indications & Dose: ANEMIA OF CHRONIC RENAL FAILURE IM Adult 50-200mg weekly | APLASTIC ANEMIA IM Adult 50-150mg weekly | AS ANABOLIC AFTER DEBILITATING ILLNESS IM Adult 25-100mg once q3-4wk | POSTMENOPAUSAL METASTATIC BREAST CARCINOMA IM Adult 25-100mg once q3-4wk | POSTMENOPAUSAL OSTEOPOROSIS IM Adult 25-100mg once q3-4wk

Contra: Hypercalciuria, men with carcinoma of the breast/prostate, nephrosis/nephrotic phase of nephritis, cardio-renal failure, hepatic disease with impaired bilirubin excretion

Precautions: CVD, renal/hepatic impairment, epilepsy, migraine, DM, conditions that aggravate by possible fluid retention/edema, risk of developing skeletal metastases, 17alpha-alkylated derivatives, children

ADR: Serious: Edema, hypercalcemia, impaired glucose tolerance, increased LDL & decreased HDL, suppression of clotting factors, GI bleeding, liver toxicity, prostatic hyperplasia, accelerate growth of malignant neoplasms of the prostate, bladder irritability, priapism, Others: gynecomastia, suppression of ovarian activity & menstruation, virilism, erythema & allergic contact dermatitis, epididymitis, headache, depression, increased hematocrit

DDI: Serious Insulin efficacy enhanced by drug

Monitor: Pregnancy test before therapy, LFTs, skeletal maturation, electrolytes, Hct/Hgb, TC, glucose in DM, bone age (children)