Nateglinide

Details About Generic Salt ::  Nateglinide 

Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System   Sub Medicine Class ::  Insulin , Anti Diabetic drugs

8D. INSULIN & ANTI-DIABETIC DRUGS in 8. ENDOCRINE/STEROID HORMONES & METABOLIC SYSTEM
NATEGLINIDE
MEGLITINIDE DERIVATIVE | ANTI-DIABETIC
PK: A: Rapid D: 10L M: Hepatic E: Urine (83%)& feces (10%)

Indications & Dose: TYPE 2 DIABETES MELLITUS PO Adult Initially & MD 120mg TID, may be given alone/combination with metformin/thiazolidinedione

Contra: Hypersensitivity, DKA, type 1 DM

Precautions: Elderly, substitute insulin during intercurrent illness, malnourished patients, hepatic impairment

ADR: Serious: Hypoglycemia, jaundice, hypersensitivity reactions, Others: headache, dizziness, pruritus, weight gain, arthropathy

DDI: Serious Itraconazole/Fluconazole modestly increases drug levels Others Rifampicin decreases drug levels

Diet: Before food (30 mins)

Monitor: Glucose, HbA1c levels, weight & lipid profile

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