NEBINEX 10 2.5MG

The Brand Name NEBINEX Has Generic Salt :: Nebivolol 

NEBINEX  Is From Company GLENMARK Priced :: Rs. 35.45

NEBINEX have Nebivolol is comes under Sub class Anti Hypertensives of  Main Class Cardiovascular System

Main Medicine Class:: Cardiovascular System  Sub Medicine Class :: Anti Hypertensives 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Nebivolol  TAB  Rs. 35.45  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 NEBINEX  GLENMARK  2.5MG  10 Rs. 35.45

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From GLENMARK :: NEBINEX  Nebivolol  Cardiovascular System Anti Hypertensives

Indications for Drugs ::

Heart failure, Hypertension

Drug Dose ::

Adult: PO HTN 5 mg/day. Max: 40 mg once daily. Heart failure Initial: 1.25 mg once daily. May double dose 1-2 wkly up to a max of 10 mg once daily.

Contraindication ::

Hepatic impairment, sick sinus syndrome, 2nd and 3rd degree heart block (without a pacemaker), history of asthma, metabolic acidosis, severe peripheral arterial disease, severe bradycardia, cardiogenic shock or decompensated heart failure, untreated phaeochromocytoma. Pregnancy and lactation.

Drug Precautions ::

Elderly. History of anaphylaxis to various allergens, 1st degree AV block, peripheral arterial disease, DM, compensated heart failure, myasthenia gravis, history of psychiatric illness, renal impairment. May mask signs of hyperthyroidism (e.g. tachycardia).

Drug Side Effects ::

Peripheral oedema, bradycardia, chest pain; headache, fatigue, dizziness, insomnia; rash; hypercholesterolaemia, decreased HDL levels, hyperuricaemia, increased triglyceride levels, increased uric acid levels; diarrhoea, nausea, abdominal pain; thrombocytopenia; paraesthesia, weakness; increased BUN; dyspnoea. Potentially Fatal: Anaphylaxis.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Nebivolol exhibits high selectivity for beta1-adrenergic receptors and has vasodilating activity due to a direct action on the endothelium, involving nitric oxide release. It lacks intrinsic sympathomimetic and membrane-stabilising activity.

Drug Interactions ::

Increased plasma concentrations w/ potent CYP2D6 inhibitors (e.g. paroxetine, fluoxetine, propafenone, thioridazine, quinidine). Concomitant use w/ antiarrhythmic drugs (e.g. amiodarone, disopyramide) or nondihydropyridine Ca channel blockers (e.g. diltiazem, verapamil) may cause conduction disturbance. Additive negative effects on AV conduction and heart rate w/ other beta-adrenergic blocking agents or digoxin. Concurrent admin w/ catecholamine-depleting agents (e.g. reserpine) may result in additive hypotension or bradycardia. Abrupt withdrawal of clonidine may increase risk of rebound HTN.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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