Nebivolol

Details About Generic Salt ::  Nebivolol 

Main Medicine Class:: Cardiovascular System   Sub Medicine Class ::  Anti Hypertensives

4D. ANTI-HYPERTENSIVES in 4. CARDIOVASCULAR SYSTEM
NEBIVOLOL
CARDIOSELECTIVE ß-BLOCKER | ANTI-HYPERTENSIVE
also comes under 4A. Drugs for Cardiac Failure & Shock in 4. Cardiovascular System
PK: A: Rapid M: Hepatic E: Urine & feces

Indications & Dose: HEART FAILURE PO Adult Initially 1.25mg/day, if tolerated double the dose q1-2wk max 10mg/day | HYPERTENSION PO Adult Initially 5mg/day, if no response increase dose after 2wk max 40mg/day Elderly >65 yr: Initially 2.5mg/day may be increased to 5mg/day if needed

Contra: pheochromocytoma, metabolic acidosis, cardiogenic shock, hypotension, severe peripheral arterial disease, second/third degree AV block, sinus bradycardia

Precautions: asthma, history of obstructive airways disease, first degree AV block

ADR: Serious: peripheral edema, bradycardia, chest pain, arthralgia, myopathies, muscle cramps, blood disorders, hypoglycemia, changes in lipid levels, Others: headache, fatigue, dizziness, insomnia, rash, bronchospasm, dyspnea, paresthesia

DDI: Serious GA potentiates hypnosis

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