NEUPENT 10 900MG(SR)

The Brand Name NEUPENT Has Generic Salt :: Gabapentin 

NEUPENT  Is From Company Solus Priced :: Rs. 277.2

NEUPENT have Gabapentin is comes under Sub class Anti Epileptics of  Main Class Nervous System

Main Medicine Class:: Nervous System  Sub Medicine Class :: Anti Epileptics 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Gabapentin  AF CAP  Rs. 277.2  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 NEUPENT  Solus  900MG(SR)  10 Rs. 277.2

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Solus :: NEUPENT  Gabapentin  Nervous System Anti Epileptics

Indications for Drugs ::

Epilepsy, Neuropathic pain, Partial Seizures, Hot flashes, Fibromyalgia, Postherpetic Neuralgia, Pain from diabetic neuropathy.

Drug Dose ::

Adult: PO: Neuropathic pain: 300 mg on day-1, then 300 mg twice on day-2, then 300 mg thrice on day-3, then increase the dose according to response in steps of 300 mg daily to maximum 1800 mg daily in three divided doses. Partial seizure/epilepsy: 300 mg on day-1, then 300 mg twice on day-2, then 300 mg thrice on day-3, then increase the dose according to response in steps of 300 mg daily to maximum 2400 mg daily in three divided doses. In case of children: For 6-12 years – 10 mg/kg on day-1, then 20 mg/kg on day-2, then 25-35 mg/kg daily in 3 divided doses. Maintenance dose is 900 mg daily (body weight 26-36 Kg) or 1.2 gm daily (body weight 37-50 Kg). Renal impairment: Haemodialysis: Loading dose: 300-400 mg followed by 200-300 mg after each 4 hr of haemodialysis. CrCl (ml/min) <15 300 mg on alternate days to daily. 15-29 300 600 30-49 300-900 50-79 600-1,800 daily. Contraindication ::

Hypersensitivity. Lactation.

Drug Precautions ::

Discontinuation or transfer from other antiepileptics, history of psychotic illness; renal impairment; pregnancy. Gradual withdrawal over at least 7 days to prevent an increase in seizure frequency.

Drug Side Effects ::

Somnolence, dizziness, ataxia, weakness, paraesthesia, fatigue, headache; nystagmus, diplopia; nausea, vomiting, wt gain, dyspepsia; rhinitis; tremor; leucopenia; altered LFTs; Stevens-Johnson syndrome.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Gabapentin is structurally related to the neurotransmitter GABA but is neither a GABA agonist nor antagonist. High affinity gabapentin binding sites are located throughout the brain. These sites correspond to the presence of voltage-gated Ca channels particularly controlling the ?-2/?-1 subunit. This channel appears to be located presynaptically and may modulate the release of excitatory neurotransmitters which participate in epileptogenesis and nociception.

Drug Interactions ::

May increase plasma level w/ morphine. Reduced absorption w/ antacids.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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