NOLVADEX 10 10MG | MedicScientist :: Total Health Portal

The Brand Name NOLVADEX Has Generic Salt :: Tamoxifen 

NOLVADEX  Is From Company Astrazeneca Priced :: Rs. 186

NOLVADEX have Tamoxifen is comes under Sub class Anti Neoplastic Agents of  Main Class Anti Neoplastic Agents

Main Medicine Class:: Anti Neoplastic Agents  Sub Medicine Class :: Anti Neoplastic Agents 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Tamoxifen  TAB  Rs. 186  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 NOLVADEX  Astrazeneca  10MG  10 Rs. 186

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Astrazeneca :: NOLVADEX  Tamoxifen  Anti Neoplastic Agents Anti Neoplastic Agents

Indications for Drugs ::

Breast cancer

Drug Dose ::

Adult: PO Breast cancer 20 mg in 1-2 divided doses. Max: 40 mg/day. Reduction of breast cancer incidence in high-risk women 20 mg/day for 5 yr. Anovulatory infertility 20 mg/day on days 2-5 of the menstrual cycle. Max: 80 mg/day. Adult: PO Breast cancer 20 mg in 1-2 divided doses. Max: 40 mg/day. Reduction of breast cancer incidence in high-risk women 20 mg/day for 5 yr. Anovulatory infertility 20 mg/day on days 2-5 of the menstrual cycle. Max: 80 mg/day.

Contraindication ::

Pregnancy and lactation. History of thromboembolic events.

Drug Precautions ::

Perform routine haematological and liver function tests in long-term therapy. Gynaecological monitoring is necessary in women.

Drug Side Effects ::

Hot flushes, oedema, fluid retention, dry skin, vaginal bleeding, vaginal discharge, pruritus vulvae, GI upsets, nausea, dizziness, rashes, blurred vision, loss of acuity, alopecia, increased liver enzymes, hypertriglyceridaemia, uterine fibroids and endometrial hyperplasia. Potentially Fatal: Blood dyscrasias, cholestasis, hepatitis, hypercalcaemia in patients with bone metastasis, thromboembolic events. Increased risk of endometrial cancer and uterine sarcoma.

Pregnancy category ::
Pregnancy category

4

Drug Mode of Action ::  

Tamoxifen, a triphenylethylene derivative, produces a nuclear complex by competitively binding to oestrogen receptors on tumours and other tissue targets thus, decreasing DNA synthesis and inhibiting oestrogen effect. It is only cytostatic rather than cytotoxic due to accumulation of cell in G0 and G1 phases.

Drug Interactions ::

Aminoglutethimide reduces plasma-tamoxifen concentration. Potentially Fatal: Concurrent use increased anticoagulant effect of warfarin; increased risk of thromboembolic events with other cytotoxic drugs.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.