The Brand Name NUCERIN Has Generic Salt :: DIACEREIN
NUCERIN Is From Company Novagen Ph. Priced :: Rs. 95
NUCERIN have DIACEREIN is comes under Sub class Drugs for Arthritis,Osteoporosis of Main Class Musculoskeletal Disorders , Pain
Main Medicine Class:: Musculoskeletal Disorders , Pain Sub Medicine Class :: Drugs for Arthritis,Osteoporosis
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Indications for Drugs ::
Rheumatoid arthritis, Osteoarthritis, Chronic low back pain
Drug Dose ::
Adults and children over 12 years and older: 1 tablet twice daily (12 hourly) taken with food.
Absorption of Diacerein is reduced if taken with aluminium and/or magnesium hydroxide antacid. Diacerein also increases risk of diarrhea if taken with laxatives, antibiotics. Avoid co-administration with fibers and phytic acids. Diacerein has shown hypersensitivity to anthraquinone derivatives.
Drug Precautions ::
Caution should be practiced when administering Diacerein + Glucosamine Sulphate in those patients who are allergic to Glucosamine and/or Diacerein or to shellfish (e.g., shrimp, crab); who have diabetes, asthma, alcohol dependence or liver disease. Before taking Diacerein + Glucosamine Sulphate complete blood count, liver function and urinalysis should be monitored regularly.
Drug Side Effects ::
Diarrhea, constipation, epigastric pain, heart burn, nausea, vomiting, headache, skin rashes, drowsiness, intense yellow coloring of urine.
Pregnancy category ::
Drug Mode of Action ::
Diacerein is an anthraquinone derivative that has been used in osteoarthritis. It is thought to act via inhibition of interleukin-1?.Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage.
Drug Interactions ::
Diacerein: Decreased absorption with aluminium and/or magnesium hydroxide antacids. Increased risk of diarrhoea with laxatives, antibiotics. Avoid co-admin with fibres and phytates. Glucosamine: May reduce effect of antidiabetic agents, doxorubicin, etoposide, tenoposide. May enhance anticoagulant activity of warfarin.