Pentoxifylline

Details About Generic Salt ::  Pentoxifylline 

Main Medicine Class:: Cardiovascular System   Sub Medicine Class ::  Drugs for Vascular disorder

4G. DRUGS FOR VASCULAR DISORDER in 4. CARDIOVASCULAR SYSTEM
PENTOXIFYLLINE
XANTHINE DERIVATIVE | VASODILATOR
PK: A: Well absorbed M: Hepatic E: Urine

Indications & Dose: INTERMITTENT CLAUDICATION PO Adult 400mg TID 8 wk, reduce to 400mg BID in case of GI/CNS adverse effects

Contra: Hypersensitivity, recent cerebral/retinal hemorrhage

Precautions: Renal impairment, elderly, children

ADR: Serious: Flushing, angina, palpitations, cardiac arrhythmias, hypersensitivity reactions, risk of bleeding, Others: Nausea, vomiting, dizziness, GI disturbances, headache

DDI: Serious Ciprofloxacin/Cimetidine increases drug levels (increases incidence of adverse effects), Acenocoumarol increases risk of serious bleeding, Antidiabetics intensifies blood glucose-lowering effects by drug (IV), Theophylline levels increases by drug

Diet: With food

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