PETHIDINE HCL VIAL 100MG/2ML | MedicScientist :: Total Health Portal

The Brand Name PETHIDINE HCL Has Generic Salt :: Pethidine 

PETHIDINE HCL  Is From Company Haffkine Priced :: Rs. 489.45

PETHIDINE HCL have Pethidine is comes under Sub class #N/A of  Main Class #N/A

Main Medicine Class:: #N/A  Sub Medicine Class :: #N/A 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Pethidine  INJ  Rs. 489.45  VIAL
Brand Name Company / Manufacturers Strength Unit Price / VIAL
 PETHIDINE HCL  Haffkine  100MG/2ML  VIAL Rs. 489.45

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Haffkine :: PETHIDINE HCL  Pethidine  #N/A #N/A

Indications for Drugs ::

Anaesthesia, Postoperative pain, Moderate to severe acute pain, Obstetric analgesia

Drug Dose ::

Adult: IV Adjunct to anesth 10-25 mg. IV/IM/SC Moderate to severe acute pain 25-100 mg IM/SC inj or 25-50 mg by slow IV inj repeated after 4 hr. IM/SC Obstetric analgesia 50-100 mg as soon as contractions occur at regular intervals; repeat after 1-3 hr if needed. Max: 400 mg/24 hr. Pre-op medication 25-100 mg 1 hr pre-op. Post-op pain25-100 mg 2-3 hrly if needed.

Contraindication ::

Hypersensitivity.

Drug Precautions ::

May impair ability to drive or operate machinery. Hypovolaemia, CV disease; adrenal insufficiency; biliary tract disorder; CNS depression or coma; history of drug abuse or acute alcoholism; head injury, intracranial lesions, elevated intracranial pressure; hepatic or renal impairment; morbidly obese; prostatic hyperplasia; toxic psychoses; pre-existing respiratory compromise (hypoxia and/or hypercapnia), COPD or other obstructive airway disease; sickle-cell disease; supraventricular tachycardia; thyroid dysfunction. Elderly and debilitated patients. Withdraw gradually. Pregnancy (avoid prolonged use or high doses at term) and lactation.

Drug Side Effects ::

Hypotension; fatigue, drowsiness, dizziness, nervousness, headache, restlessness, malaise, confusion, depression, hallucinations, tremors, muscle twitches, increased intracranial pressure, seizure, serotonin syndrome; rash, urticaria; nausea, vomiting, constipation, anorexia, stomach cramps, xerostomia, biliary spasm, paralytic ileus, sphincter of Oddi spasm; ureteral spasms, decreased urination; pain at inj site; weakness; dyspnoea; histamine release, physical and psychological dependence.

Pregnancy category ::
Pregnancy category

4

Drug Mode of Action ::  

Pethidine is a phenylpiperidine derivative opioid analgesic. It acts mainly as mu-receptor agonist. Like most, opioid analgesics, it mimics endogenous opioids by activating opioid receptors in the central and peripheral nervous system. It reduces the release of neurotransmitter substances and also reduces the activity of postsynaptic neurons in the spinal cord thus preventing transmission of pain impulse.

Drug Interactions ::

W/in 2 wk of MAOIs or moclobemide, selegiline, ritonavir, cimetidine, CNS depressants, barbiturate salts, aminophylline, heparin, methicillin, morphine, nitrofurantoin, phenytoin, sulphadiazine, Na iodide, sulphafurazole diethanolamine, acyclovir, imipenem, frusemide, idarubicin, minocycline, tetracycline, cefoperazone, mezlocillin, nafcillin, liposomal doxorubicin.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.