Phenoxybenzamine

Details About Generic Salt ::  Phenoxybenzamine 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

4A. DRUGS FOR CARDIAC FAILURE & SHOCK in 4. CARDIOVASCULAR SYSTEM
PHENOXYBENZAMINE
A-ADRENERGIC BLOCKER | ANTI-HYPERTENSIVE IN PHEOCHROMOCYTOMA
also comes under 4D. Anti-Hypertensives in 4. Cardiovascular System,  ,   10C. Drugs For Prostate Disorders in 10. Genito-Urinary System
PK: A: Incomplete & variable M: Hepatic E: Urine; bile

Indications & Dose: HYPERTENSION IN PHEOCHROMOCYTOMA PO Adult Initially 10mg OD/BID, increased gradually according to the response to usual dose 1-2mg/kg/day in 2 divided doses Child 1 month–18 yr: 0.5–1mg/kg BID adjusted according to response | IV Adult Inf: 1mg/kg/day over 2h Child Inf: 1 month–18 yr: 0.5–1 mg/kg/day may be adjusted according to response up to 2mg/kg/day200 mL of 0.9% Nacl | SEVERE SHOCK IV Adult Inf: 1mg/kg/day over 2hin 200-500mL 0.9% Nacl | URINARY RETENTION DUE TO NEUROGENIC BLADDER PO Adult 10mg BID

Contra: Porphyria

Precautions: HF, IHD, cerebrovascular disease, renal impairment, stop drug if severe hypotension occurs

ADR: Serious: Orthostatic hypotension, convulsions, inhibition of ejaculation, idiosyncratic profound hypotension, Others: sweating, dizziness, reflex tachycardia, nasal congestion, miosis

Related Posts:
You May Also Like::