Phenylpropanolamine

Details About Generic Salt ::  Phenylpropanolamine 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM
PHENYLPROPANOLAMINE
INDIRECTLY-ACTING SYMPATHOMIMETIC | NASAL DECONGESTANT
PK: A: Rapid & complete M: Hepatic E: Urine

Indications & Dose: NASAL CONGESTION PO Adult Modified release: up to 50mg bid

Contra: pheochromocytoma, severe HTN

Precautions: Hyperthyroidism, occlusive vascular disease, CVD, obstructive cardiomyopathy, angle-closure glaucoma, prostate disorders

ADR: Serious: hypertensive episodes, dyspnea, difficulty in micturition & urinary retention, piloerection, reflex bradycardia, tachycardia, palpitations, increased cardiac contractility, Others: sweating, vomiting, anxiety, fear, restlessness, insomnia, confusion, headache

DDI: Serious Bromocriptine causes HTN, severe headache, seizures & psychosis, Indinavir causes hypertensive crisis, MAOIs causes potentially fatal hypertensive crisis, Amantadine causes psychosis, Theophylline clearance reduces, Methyl dopa/Caffeine/Oxprenolol leads to HTN

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