The Brand Name PREGTAR Has Generic Salt :: Ritodrine
PREGTAR Is From Company Shreeyam Priced :: Rs. 85
PREGTAR have Ritodrine is comes under Sub class Tocolytics of Main Class Reproductive System
Main Medicine Class:: Reproductive System Sub Medicine Class :: Tocolytics
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Indications for Drugs ::
Drug Dose ::
By intravenous infusion Initially 50 micrograms/minute, increased gradually according to response by 50 micrograms/minute every 10 minutes until contractions stop or maternal heart rate reaches 140 beats/minute; continue for 12–48 hours after contractions cease (usual rate 150–350 micrograms/minute); maximum rate 350 micrograms/minute. Intramuscular injection 10 mg in every 3–8 hours continued for 12–48 hours after contractions have ceased; then by mouth. Oral maintenance treatment One tablet (10 mg) may be given approximately 30 minutes before termination of intravenous therapy, repeated every 2 hours for 24 hours, followed by 10–20 mg every 4–6 hours, maximum oral dose 120 mg daily.
It is contraindicated in patients with known hypersensitivity to the active ingredient or any of the excipients of this component. ?2–agonists are contra-indicated in cardiac disease and in patients with significant risk factors for myocardial ischaemia; they should also be avoided in antepartum haemorrhage, intra-uterine infection, intra-uterine fetal death, placenta praevia, abruptio placenta, threatened miscarriage, cord compression, and eclampsia or severe pre-eclampsia.
Drug Precautions ::
It should be used cautiously in patient with suspected cardiac diseases, hypertension, hyperthyroidism, hypokalaemia, diabetes mellitus, mild to moderate preeclampsia, monitor blood pressure and pulse rate and avoid over-hydration during taking ritodrine hydrochloride.
Drug Side Effects ::
The common side-effects of ritodrine hydrochloride are nausea, vomiting, flushing, sweating, tremor, hypokalaemia, tachycardia, palpitations, hypotension (left lateral position throughout infusion to minimize risk), uterine bleeding, pulmonary oedema; chest pain or tightness, arrhythmias and salivary gland enlargement. On prolonged administration for several weeks may cause leucopenia and agranulocytosis; liver function abnormalities including increased transaminases and hepatitis.
Pregnancy category ::
Drug Mode of Action ::
A selective beta 2-adrenoceptor agonist with its main action on the uterus, causing relaxation. It reduces the intensity and frequency of contractions. Heart rate is also increased while diastolic pressure is reduced. May cause bronchial relaxation but this is not clinically significant in its usage.
Drug Interactions ::
May enhance neuromuscular blockade produced by pancuronium and vecuronium. Potentially Fatal: Potassium-depleting drugs may increase risk of hypokalaemia.