Primaquine

Details About Generic Salt ::  Primaquine 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

13J. ANTI-MALARIALS in 13. ANTI-INFECTIVES
PRIMAQUINE
8-AMINOQUINOLINE | ANTIMALARIAL
PK: A: Well absorbed D: Extensive M: Hepatic E: Urine

Indications & Dose: P. FALCIPARUM MALARIA PO Adult 750µg/kg single dose, max 45mg | RADICAL CURE OF VIVAX OR OVALE MALARIA PO Adult 15mg of base/day 2 wk (15mg base= 26.4mg primaquine phosphate)

Contra: hypersensitivity, bone marrow depression

Precautions: G6PD deficiency patients

ADR: Serious: methemoglobinemia

DDI: Serious Primaquine increases risk of toxicity

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