Primary Hypertension due to Endocrine adrenal Hypertension Adrenogenital syndrome Oral Contraceptives

Endocrine HypertensionGlycogen Storage Diseases von Gierke disease, Andersen's disease, McArdle's disease. Read more ... » adrenal Hypertension

Cushing’s S ndrorne :

Adrenogenital syndrome:

  • In adrenogenital syn­drome there is C – 11 or C-17 hydroxylase deficiency and increased production of deoxycorticosterone re­sulting in increased sodium retention with hyperten­sion and decreased PRA (Plasma Renin Activity).

PheochromocytomaPheochromocytoma Clinical Features Diagnosis Treatment. Read more ... » :

Acromegaly :

Hypercalcemia :

    • High calcium blood level is associated with increased incidence of hypertension.
    • Calcium entry blockers are effective antihypertensive agents.
  •  In’ hyperparathyroidism there is nephrolithiasis, nephrocalcinosis as a result of which there is renalDiabetic Nephropathy and Renal complications of DM (Diabetes Mellitus). Read more ... » parenchymal damage and hyperten­sion. Increased calcium levels have direct vasocon­strictor effect also. High intake of calcium is associ­ated with decreased incidence of hypertension.

Oral Contraceptives

  • Estrogen containing oral contraceptives causes hy­pertension.
  • In OC with low dose estro en, activation of renin an­giotensin aldosteroneLABORATORY TESTS FOR ADRENAL FUNCTIONS. Read more ... » mechanfsm is responsible for nypertension.
  • Due to angiotensin II there is potent vasoconstrictor effect.
  • Due to aldosterone, blood volume increases leading to hypertension.
  • Estrogen stimulates hepatic synthesis of renin sub­strat~-angioten§inog~n so there is increased produc­~ of angiotensin II and secondary aldosteronism.
  • Some women develop hypertension with use of oral contraceptive if they are more than 35 yrs age, obese, there is high estrogen content of oral contraceptive, mild renal diseaseCONTRACEPTION TEMPORARY METHODS OF CONTRACEPTION. Read more ... », increased vascular sensitivity to estrogen or angiotensin II, family history of hyper­tension.

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